When you buy a can of 2400 Alliant Smokeless Powder, you can rest assured that it has been subjected to the same rigorous quality assurance standards as the rest of the industry has been using for the past century. Maintaining consistency in chemical make-up, grain shape and size, and overall density are all part of the routine testing done in a ballistics lab.
Magnum-44 Smokeless powder, such as 2400, works well with high-quality handgun cartridges such as the Remington and others. The 2400 is compatible with a wide variety of cartridges, not just the 22 Hornet. This includes the 218 Bee and the 410 Bore.
Warnings from the Manufacturer:
Reloading guide loads should not be exceeded at any time.
Don’t combine different powders, no matter how similar they may seem.
Black powder and its equivalents should never be used in place of smokeless powder.